2012

January

Justin Lathia, PhD starts the lab.

Meizhang Li, PhD joins the lab as a postdoctoral fellow.

James Hale, PhD joins the lab as a postdoctoral fellow.

July

Alvaro Alvarado joins the lab as a graduate student (Molecular Medicine, Cleveland Clinic).

Maksim Sinyuk joins the lab as a graduate student (Cleveland State).

September

Kevin Stoltz joins the lab as a technician.

2013

October

Praveena S Thiagarajan, MD, PhD joins the lab as a postdoctoral fellow.

September

Erin Mulkearns-Hubert, PhD joins the lab as a postdoctoral fellow.

July

Meizhang Li, PhD leaves the lab to join Yunnan University as a professor.

February

Balint Otvos, PhD joins the lab as a medical student (Case Western).

2014

June

Balint Otvos, MD, PhD leaves the lab to start medical residency (Neurosurgery, Cleveland Clinic).

Kevin Stoltz leaves the lab to start graduate school at University of Alabama Birmingham.

July

Published Cancer stem cell-specific scavenger receptor CD36 drives glioblastoma progression (Stem Cells)

December

Daniel Silver, PhD joins the lab as a postdoctoral fellow.

2015

May

Published Differential connexin function enhances self-renewal in glioblastoma (Cell Reports).

April

Published Development of a fluorescent reporter system to delineate cancer stem cells in triple-negative breast cancer (Stem Cells) with Ofer Reizes, PhD.

March

Published Cx43 expression is associated with increased malignancy in prostate cancer cell lines and functions in a gap junction independent mechanism to suppress migration (Oncotarget).

Published Development of a Sox2 reporter system modeling cellular heterogeneity in glioma (Neuro-Oncology).

February

Caner Saygin, MD joins the lab as research scholar. Co-mentored with Ofer Reizes, PhD.

June

Soumya Turaga, MS, BS joins the lab as a graduate student (Cleveland State).

Luke Torre-Healy joins the lab as a technician.

September

Anastasia Chumakova, MD joins the lab as a postdoctoral fellow.

October

Published Cx25 contributes to leukemia cell communication and chemosensitivity (Oncotarget).

2016

August

Published Cancer stem cell-secreted macrophage migration inhibitory factor stimulates myeloid derived suppressor cells function and facilitates glioblastoma immune evasion (Stem Cells).

May

Maksim Sinyuk, PhD leaves the lab to the Jessica Williams lab (Lerner) as a postdoctoral fellow.

Alvaro Alvarado, PhD leaves the lab to join UCLA as a postdoctoral fellow.

Published Cisplatin induces stemness in ovarian cancer (Oncotarget).

Published Coordination of self-renewal in glioblastoma by integration of adhesion and microRNA signaling (Neuro-Oncology).

March

Praveena S Thiagarajan, MD, PhD is promoted to Research Associate (faculty position).

February

Tyler Alban, BS joins the lab as a graduate student (Molecular Medicine, Lerner).

2017

April

Published Glioblastoma cancer stem cells evade innate immune suppression of self-renewal through reduced TLR4 expression (Cell Stem Cell).

May

Praveena S Thiagarajan, MD, PhD leaves the lab to start medical residency.

June

Caner Saygin, MD leaves the lab to start medical residency.

Luke Torre-Healy, BS leaves the lab to join medical school (MD/PhD Program, Stony Brook University).

July

Josephine Volovetz, BS joins the lab as a medical student for her thesis year (CCLCM, Cleveland Clinic).

October

Defne Bayik, PhD joins the lab as a postdoctoral fellow.

September

Published CD55 regulates self-renewal and cisplatin resistance in endometroid tumors (Journal of Experimental Medicine) with Ofer Reizes, PhD.

August

Published STAT3 activation by leptin receptor is essential for TNBC stem cell maintenance (Endocrine Related Cancer) with Ofer Reizes, PhD.

2018

February

Published Cx26 drives self-renewal in triple-negative breast cancer via interaction with NANOG and focal adhesion kinase (Nature Communications) with Ofer Reizes, PhD.

June

Josephine Volovetz, MD leaves the to start medical residency (Neurosurgery, Cleveland Clinic).

July

Adam Lauko, BS joins the lab as a graduate student (MSTP, Case Western).

Katie Troike, MS, BS joins the lab as a graduate student (Molecular Medicine, Cleveland Clinic)

Matthew Grabowski, MD joins the lab as a Research Fellow (Cleveland Clinic).

Balint Otvos, MD, PhD joins the lab as a neurosurgery resident (Cleveland Clinic).

November

Published Global immune fingerprinting in glioblastoma reveals immune-suppression signatures associated with prognosis (JCI Insight).

2019

June

Anastasia Chumakova, MD leaves the lab to start medical residency (UC Irvine)

Gustavo Roversi, BS joins the lab as a technician.

Published Therapeutic strategies to induce Era in luminal breast cancer to enhance tamoxifen efficacy (Endocrine Related Cancer) with Ofer Reizes, PhD.

April

Published Development of a Cx46 targeting strategy for cancer stem cells (Cell Reports).

March

James Hale, PhD leaves the lab to join the Case Comprehensive Cancer Center as the Assistant Director of Research Programs.

Published High-throughput Automated Single Cell Imaging Analysis Reveals Dynamics Of Glioblastoma Stem Cell Population During State Transition (Cytometry Part A).

February

Kelly Mitchell, PhD joins the lab as a postdoctoral fellow.

July

Erin Mulkearns-Hubert, PhD is promoted to Research Associate (faculty position).

August

Published ADAMDEC1 maintains a growth factor signaling loop in cancer stem cells (Cancer Discovery).

November

Published Metronomic capecitabine as an immune modulator in glioblastoma patients reduces myeloid-derived suppressor cells (JCI Insight).

December

Soumya Turaga, PhD successfully defends her thesis and leaves the lab to join the University of Kansas Medical school as a postdoctoral fellow.

September

Sadie Johnson, RVT joins the lab as a research technician.

2020

June

Published JAM-A functions as a female microglial tumor suppressor in glioblastoma (Neuro-Oncology).

Published Glioblastoma myeloid-derived suppressor cell subsets express differential macrophage migration inhibitory receptor profiles that can be targeted to reduce immune suppression (Frontiers in Immunology).

June

Balint Otvos, MD, PhD leaves the lab to start neurosurgery fellowship.

Grace Ahuja, BS joins the lab as a technician.

Gustavo Roversi, BS leaves the lab to start medical school (CCLCM).

May

Tyler Alban, PhD, successfully defends his thesis and leaves the lab to join the Tim Chan lab (Lerner) as a postdoctoral fellow.

February

Published Identifying conserved molecular targets required for cell migration of glioblastoma cancer stem cells (Cell Death and Disease).

July

Kristen Kay, BS, joins the lab as a graduate student (Molecular Medicine, Cleveland Clinic).

August

Juyeun Lee, DVM, PhD joins the lab as a postdoctoral fellow.

Published Myeloid-derived suppressor cell subsets drive glioblastoma growth in a sex-specific manner (Cancer Discovery).

September

Dionysios Watson, MD, PhD joins the lab as a fellow.

November

Published Hepatobiliary malignancies have distinct peripheral myeloid-derived suppressor cell signatures and tumor myeloid cell profiles (Scientific Reports).

December

Published Asymmetric division promotes therapeutic resistance in glioblastoma stem cells (JCI Insight).

2021

June

Grace Ahuja, BS leaves the lab to start medical school.

May

Matthew Grabowski, MD is promoted to Associate Staff (faculty position).

February

Published Preclinical modeling of surgery and steroid therapy for glioblastoma reveals changes in immunophenotype that are associated with tumor growth and outcome (Clinical Cancer Research).

January

Published Development of near-infrared imaging agents for detection of junction adhesion molecule-A protein (Translational Oncology).

July

Sabrina Wang, BS joins the lab as a graduate student (MSTP, Case Western).

Published Severe consequences of a high-lipid diet include hydrogen sulfide dysfunction and enhanced aggression in glioblastoma (Journal of Clinical Investigation).

September

Published The translocator protein (TSPO) genetic polymorphism A147T is associated with worse survival in male glioblastoma patients (Cancers).

October

Dan Silver, PhD, is promoted to Research Associate (faculty position).

August

Salma Ben-Salem, PhD, joins the lab as a postdoctoral fellow.

Samuel Sprowls, PhD joins the lab as a postdoctoral fellow.

Kelly Mitchell, PhD leaves the lab to join the Fred Hutchinson Cancer Research Center.

2022

August

Katie Troike, MS, PhD successfully defends her thesis and leaves the lab to start her clinical chemistry fellowship.

July

Nicole Hajdari, BA joins the lab as a research technologist.

Josie Volovetz, MD joins the lab as a graduate student (PRISM, Cleveland Clinic).

June

Adam Lauko, PhD successfully defends his thesis and leaves the lab to enter M3 year (MSTP, Case Western).

January

Lathia Lab turns 10!

Sadie Johnson, RVT is promoted to Research Technologist.

November

Defne Bayik-Watson, PhD leaves the lab to start her lab at the University of Miami.

Dennis Watson, MD, PhD leaves the lab to start his lab at the University of Miami.

Salma Ben-Salem, PhD leaves the lab to pursue a career in industry.
Sabré Randall, BS joins the lab as a research technologist.

December

Anthony Sloan, PhD joins the lab as a postdoctoral fellow.

September

Andrea Alvarez, MS joins the lab as a visiting student researcher.

other milestones and fun things

updated often.

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